Anti-Mouse PD-L1 Recombinant Nanobody (C3) (MV974033)

价格:

规格：

50ug
100ug
1mg

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号

MV974033

品牌

abinScience

描述

Anti-Mouse CD274/PD-L1/B7-H1 Nanobody (C3) [C3] (MV974033) is a alpaca monoclonal antibody detecting B7-H1 in ELISA, FuncS. Suitable for Mouse.

种属反应性

Mouse

应用

ELISA, FuncS, WB

宿主

Alpaca

同种型

VHH-8His-Cys-tag

克隆号

克隆类型

Monoclonal

经测试应用

靶标

B7 homolog 1, CD274, Pdcd1lg1, PDCD1 ligand 1, B7h1, Programmed death ligand 1, B7-H1, PD-L1, Cd274, Pdl1, Programmed cell death 1 ligand 1, Pdcd1l1

内毒素水平

Please contact with the lab for this information.

纯度

>95% as determined by SDS-PAGE.

纯化方式

Purified by Nickel column.

Accession号

Q9EP73

状态

Liquid

保存溶液

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

背景

Programmed cell death 1 ligand 1 (CD274/PD-L1) is a ~32 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. As a ligand for the inhibitory receptor PDCD1/PD-1, modulates the activation threshold of T-cells and limits T-cell effector response. Through a yet unknown activating receptor, may costimulate T-cell subsets that predominantly produce interleukin-10 (IL10). CD274 is the therapeutic target of atezolizumab (Tecentriq) and durvalumab (Imfinzi).

1. Tamura, H. et al. (2001) Blood 97, 1809-16. PMID: 11238124

2. Freeman, GJ. et al. (2000) The Journal of experimental medicine 192, 1027-34. PMID: 11015443

3. Wang, S. et al. (2003) The Journal of experimental medicine 197, 1083-91. PMID: 12719480

Note

For research use only.

图片

SDS-PAGE

SDS-PAGE for Anti-Mouse CD274/PD-L1/B7-H1 Nanobody (C3)
Bioactivity

Detects recombinant mouse PDL1 (Catalog No: MV974011) in indirect ELISA.
Western blot

Western blot analysis was performed using anti-PDL1 monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant mouse PDL1 (Catalog No: MV974011)

参考文献

产品说明书

Anti-Mouse PD-L1 Recombinant Nanobody (C3).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse PD-L1 Recombinant Nanobody (C3) (MV974033)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Mouse PD-L1 Recombinant Nanobody (C3) (MV974033)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价