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Anti-Human CD37 Recombinant Antibody (SAA2108) (HY564023)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

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  • 参考文献

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概述
货号HY564023
品牌abinScience
种属反应性Human
应用ELISA, WB
同种型IgG1, kappa
克隆号SAA2108
经测试应用WB
靶标Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P11049
RRIDAnti-Human CD37/TSPAN26 Antibody (SAA2108) (abinScience Cat# HY564023, RRID:AB_3729395)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Leukocyte antigen CD37 (TSPAN26) is a ~31 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Upon ligand binding, two signaling pathways are activated, one acting through phosphorylation by LYN leading to cell death or a survival pathway with activation of GSK3B. Plays an essential role essential for clustering of integrin ITGA4/ITGB1 and promotes its mobility in the plasma membrane of B-cells. In turn, participates in ITGA4/ITGB1 integrin-mediated antiapoptotic signaling through AKT.

1. Lapalombella, R. et al. (2012) Cancer cell 21, 694-708. PMID: 22624718
2. de Winde, CM. et al. (2016) The Journal of clinical investigation 126, 653-66. PMID: 26784544
3. Meyer-Wentrup, F. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 154-62. PMID: 17182550
NoteFor research use only.
Isotype ControlHuman IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
图片
  • Bioactivity

    SEC-HPLC detection for Anti-Human CD37/TSPAN26 Antibody (ABS1208).

  • SDS-PAGE

    SDS-PAGE for Anti-Human CD37/TSPAN26 Antibody (SAA2108).

  • Western blot

    Western blot analysis was performed using anti-CD37 monoclonal antibody at 1ug/mL on various samples.
    Lane 1: recombinant human CD37 (Catalog No: HY564012)
    Lane 2: negative control

  • Bioactivity

    Detects recombinant human CD37 (Catalog No: HY564012) in indirect ELISA

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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