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InVivoMAb Anti-Human APOC3 Antibody (Iv0249) (HF594010)

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规格：
  • 100ug
  • 1mg
数量：
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概述
货号HF594010
品牌abinScience
描述
InVivoMAb Anti-Human ApoC3 Antibody (Iv0249) [Iv0249] (HF594010) is a human monoclonal antibody detecting Apolipoprotein C-III in ELISA, FuncS. Suitable for Human.
种属反应性Human
应用ELISA, FuncS
同种型IgG1, kappa
克隆号Iv0249
靶标Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3, APOC3
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
相关产品 pH 7.4 Dilution Buffer
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P02656
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Apolipoprotein C-III (ApoC3) is a ~10 kDa protein. Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma. Plays a multifaceted role in triglyceride homeostasis. Intracellularly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellularly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors. Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners.

1. Chan, DC. et al. (2008) International journal of clinical practice 62, 799-809. PMID: 18201179
2. Yao, Z. et al. (2012) Current opinion in lipidology 23, 206-212. PMID: 22510806
3. Gangabadage, CS. et al. (2008) The Journal of biological chemistry 283, 17416-27. PMID: 18408013
NoteFor research use only. Not suitable for clinical or therapeutic use.
Isotype ControlHuman IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507)
图片

  • SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-Human ApoC3 Antibody (Iv0249).

参考文献
产品说明书
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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