Anti-Human JMJD6 IP Recombinant Antibody (SAA0203) (HP634013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HP634013

abinScience

种属反应性

Human

ELISA, IF, IP

Mouse

Monoclonal

SAA0203

Histone arginine demethylase JMJD6, Phosphatidylserine receptor, JmjC domain-containing protein 6, JMJD6, PTDSR, PSR, Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6, Jumonji domain-containing protein 6, Protein PTDSR, Peptide-lysine 5-dioxygenase JMJD6, Lysyl-hydroxylase JMJD6, KIAA0585

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q6NYC1

Anti-Human JMJD6 IP Antibody (SAA0203) (abinScience Cat# HP634013, RRID:AB_3729737)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 is a ~46 kDa protein. Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. Plays a role in the regulation of nucleolar liquid-liquid phase separation (LLPS) by post-translationally modifying LIAT1 at its lysine-rich domain which inhibits LIAT1 nucleolar targeting.

1. Chang, B. et al. (2007) Science (New York, N.Y.) 318, 444-7. PMID: 17947579

2. Mantri, M. et al. (2010) Journal of molecular biology 401, 211-22. PMID: 20684070

3. Hahn, P. et al. (2010) PloS one 5, e13769. PMID: 21060799

4. Han, G. et al. (2012) Journal of cellular biochemistry 113, 1663-70. PMID: 22189873

5. Poulard, C. et al. (2014) PloS one 9, e87982. PMID: 24498420

6. Webby, CJ. et al. (2009) Science (New York, N.Y.) 325, 90-3. PMID: 19574390

7. Hong, X. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 14568-72. PMID: 20679243

8. Konuma, T. et al. (2017) Scientific reports 7, 16272. PMID: 29176719

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human JMJD6 IP Antibody (SAA0203)

产品说明书

Anti-Human JMJD6 IP Recombinant Antibody (SAA0203).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JMJD6 IP Recombinant Antibody (SAA0203) (HP634013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human JMJD6 IP Recombinant Antibody (SAA0203) (HP634013)

概述

图片

参考文献

产品说明书

相关产品推荐

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