Anti-Human KDM4A IP Recombinant Antibody (SAA0204) (HF843013)

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规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HF843013

abinScience

种属反应性

Human

ELISA, IF, IP

IgG2a

SAA0204

Lysine-specific demethylase 4A, JMJD2, Jumonji domain-containing protein 2A, KDM4A, KIAA0677, JHDM3A, [histone H3]-trimethyl-L-lysine(9) demethylase 4A, [histone H3]-trimethyl-L-lysine(36) demethylase 4A, JMJD2A, JmjC domain-containing histone demethylation protein 3A

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O75164

Anti-Human KDM4A IP Antibody (SAA0204) (abinScience Cat# HF843013, RRID:AB_3729738)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Lysine-specific demethylase 4A (KDM4A/JMJD2A) is a ~120 kDa protein. Histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Also able to demethylate histone H1-4 methylated at 'Lys-26' (H1.4K26me1, H1.4K26me2 and H1.4K26me3).

1. Whetstine, JR. et al. (2006) Cell 125, 467-81. PMID: 16603238

2. Bavetsias, V. et al. (2016) Journal of medicinal chemistry 59, 1388-409. PMID: 26741168

3. Tan, MK. et al. (2011) Molecular and cellular biology 31, 3687-99. PMID: 21768309

4. Trojer, P. et al. (2009) The Journal of biological chemistry 284, 8395-405. PMID: 19144645

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human KDM4A IP Antibody (SAA0204)

产品说明书

Anti-Human KDM4A IP Recombinant Antibody (SAA0204).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM4A IP Recombinant Antibody (SAA0204) (HF843013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human KDM4A IP Recombinant Antibody (SAA0204) (HF843013)

概述

图片

参考文献

产品说明书

相关产品推荐

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