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Anti-Human KDM5C IP Recombinant Antibody (SAA0206) (HW795013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
  • 概述

  • 图片

  • 参考文献

  • 产品说明书

概述
货号HW795013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP
同种型IgG
克隆号SAA0206
靶标DXS1272E, Protein Xe169, Protein SmcX, JARID1C, [histone H3]-trimethyl-L-lysine(4) demethylase 5C, XE169, SMCX, Lysine-specific demethylase 5C, KDM5C, Jumonji/ARID domain-containing protein 1C, Histone demethylase JARID1C
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号P41229
RRIDAnti-Human KDM5C IP Antibody (SAA0206) (abinScience Cat# HW795013, RRID:AB_3729740)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Lysine-specific demethylase 5C (KDM5C) is a ~175 kDa protein. Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Represses the CLOCK-BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2.

1. Tumber, A. et al. (2017) Cell chemical biology 24, 371-380. PMID: 28262558
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human KDM5C IP Antibody (SAA0206)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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