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Anti-Human PRMT3 IP Recombinant Antibody (SAA0218) (HT002013)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HT002013
品牌abinScience
种属反应性Human
应用ELISA, IF, IP, WB
宿主Mouse
克隆类型Monoclonal
同种型IgG1
克隆号SAA0218
靶标PRMT3, HRMT1L3, Protein arginine N-methyltransferase 3, Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3
内毒素水平Please contact with the lab for this information.
纯度>95% as determined by SDS-PAGE.
纯化方式Protein A/G purified from cell culture supernatant.
Accession号O60678
RRIDAnti-Human PRMT3 IP Antibody (SAA0218) (abinScience Cat# HT002013, RRID:AB_3729752)
状态Liquid
保存溶液 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:2000-1:20000
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
背景

Protein arginine N-methyltransferase 3 (PRMT3) is a ~59 kDa protein. Protein-arginine N-methyltransferase that catalyzes both the monomethylation and asymmetric dimethylation of the guanidino nitrogens of arginine residues in target proteins, and therefore falls into the group of type I methyltransferases. Catalyzes the asymmetric arginine dimethylation at multiple sites in the Arg/Gly-rich region of small ribosomal subunit protein uS5/RPS2. Also appears to methylate other ribosomal proteins. May regulate retinoic acid synthesis and signaling by inhibiting ALDH1A1 retinal dehydrogenase activity. Contributes to methylation of histone H4 'Arg-3', a specific tag for epigenetic transcriptional activation.

1. Siarheyeva, A. et al. (2012) Structure (London, England : 1993) 20, 1425-35. PMID: 22795084
2. Liu, F. et al. (2013) Journal of medicinal chemistry 56, 2110-24. PMID: 23445220
3. Kaniskan, HÜ. et al. (2015) Angewandte Chemie (International ed. in English) 54, 5166-70. PMID: 25728001
4. Min, Z. et al. (2019) Cell death & disease 10, 581. PMID: 31378783
5. Verma, M. et al. (2021) Communications biology 4, 109. PMID: 33495566
6. Gupta, S. et al. (2024) The Biochemical journal 481, 1723-1740. PMID: 39513743
NoteFor research use only.
图片
  • SDS-PAGE

    SDS-PAGE for Anti-Human PRMT3 IP Antibody (SAA0218)

参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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