Anti-Human EP300 IP Recombinant Antibody (SAA0246) (HC510013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC510013

abinScience

种属反应性

Human

ELISA, IF, IP, IP-MS

SAA0246

Histone crotonyltransferase p300, Protein lactyltransferas p300, Protein propionyltransferase p300, Histone acetyltransferase p300, Protein 2-hydroxyisobutyryltransferase p300, EP300, p300 HAT, Histone butyryltransferase p300, P300, E1A-associated protein p300

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q09472

Anti-Human EP300 IP Antibody (SAA0246) (abinScience Cat# HC510013, RRID:AB_3729780)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Histone acetyltransferase p300 (EP300) is a ~264 kDa protein. Functions as a histone acetyltransferase and regulates transcription via chromatin remodeling. Acetylates all four core histones in nucleosomes. Histone acetylation gives an epigenetic tag for transcriptional activation. Mediates acetylation of histone H3 at 'Lys-122' (H3K122ac), a modification that localizes at the surface of the histone octamer and stimulates transcription, possibly by promoting nucleosome instability. Mediates acetylation of histone H3 at 'Lys-18' and 'Lys-27' (H3K18ac and H3K27ac, respectively).

1. Tropberger, P. et al. (2013) Cell 152, 859-72. PMID: 23415232

2. Delvecchio, M. et al. (2013) Nature structural & molecular biology 20, 1040-6. PMID: 23934153

3. Tian, Y. et al. (2025) Nature 641, 779-787. PMID: 40240600

4. Ogryzko, VV. et al. (1996) Cell 87, 953-9. PMID: 8945521

5. Jin, Q. et al. (2011) The EMBO journal 30, 249-62. PMID: 21131905

6. Hatzi, K. et al. (2013) Cell reports 4, 578-88. PMID: 23911289

8. Iioka, T. et al. (2003) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 18, 1419-29. PMID: 12929931

9. Yuan, ZL. et al. (2005) Science (New York, N.Y.) 307, 269-73. PMID: 15653507

10. Ray, S. et al. (2005) Gastroenterology 129, 1616-32. PMID: 16285960

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human EP300 IP Antibody (SAA0246)

产品说明书

Anti-Human EP300 IP Recombinant Antibody (SAA0246).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EP300 IP Recombinant Antibody (SAA0246) (HC510013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human EP300 IP Recombinant Antibody (SAA0246) (HC510013)

概述

图片

参考文献

产品说明书

相关产品推荐

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