Anti-Human TRIM28 IP Recombinant Antibody (SAA0249) (HC420013)

价格:

规格：

50ug
100ug
1mg

数量：

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概述
图片
参考文献
产品说明书

HC420013

abinScience

种属反应性

Human

ELISA, IF, IP

SAA0249

TIF1-beta, Tripartite motif-containing protein 28, KRAB-associated protein 1, TRIM28, RING-type E3 ubiquitin transferase TIF1-beta, KRAB-interacting protein 1, KRIP-1, E3 SUMO-protein ligase TRIM28, RNF96, Nuclear corepressor KAP-1, TIF1B, Transcription intermediary factor 1-beta, KAP1, KAP-1, RING finger protein 96

内毒素水平

Please contact with the lab for this information.

>95% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

Q13263

Anti-Human TRIM28 IP Antibody (SAA0249) (abinScience Cat# HC420013, RRID:AB_3729783)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Transcription intermediary factor 1-beta (TRIM28) is a ~88 kDa protein. Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression. Recruitment of SETDB1 induces heterochromatinization. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of ORM1.

1. Huang, C. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 190, 4470-3. PMID: 23543754

2. Serra, RW. et al. (2014) eLife 3, e02313. PMID: 24623306

3. Valle-García, D. et al. (2016) Epigenetics 11, 398-414. PMID: 27029610

For research use only.

SDS-PAGE

SDS-PAGE for Anti-Human TRIM28 IP Antibody (SAA0249)

产品说明书

Anti-Human TRIM28 IP Recombinant Antibody (SAA0249).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM28 IP Recombinant Antibody (SAA0249) (HC420013)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TRIM28 IP Recombinant Antibody (SAA0249) (HC420013)

概述

图片

参考文献

产品说明书

相关产品推荐

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