Anti-GTPBP1 Polyclonal Antibody (HA399014)

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100ug

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概述
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参考文献
产品说明书

概述

货号

HA399014

品牌

abinScience

描述

Anti-GTPBP1 Polyclonal Antibody (HA399014) is a rabbit polyclonal antibody detecting GTPBP1 in WB, IHC, ELISA. Suitable for Human, Mouse, Rat, Bovine, and .

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

WB, IHC, ELISA

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human GTPBP1 (Thr71-Ser384).

靶标

GTPBP1

内毒素水平

Please contact with the lab for this information.

纯度

>95% purity as determined by SDS-PAGE.

纯化方式

Purified by antigen affinity column.

Accession号

O00178

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

GTPBP1, GTP-binding protein 1, G-protein 1, GP-1, GP1, GTPBP1

背景

GTP-binding protein 1 (GTPBP1) is a ~72 kDa protein. GTPase that plays a role in the elongation phase of protein synthesis by forming ternary complexes with GTP and aminoacyl-transfer RNAs (aa-tRNAs), and delivering aa-tRNAs to the ribosomal A site in a GTP-dependent manner. Is also able to deliver deacylated tRNA to the A site. Additionally, it is involved in RNA quality control; after GTP hydrolysis, which is not immediately followed by rapid peptide bond formation, GTPBP1 likely retains aa-tRNA in the A site and promotes exosomal degradation of faulty mRNAs engaged in 80S elongation complexes. Plays a role in the regulation of circadian mRNA stability.

1. Zinoviev, A. et al. (2018) Genes & development 32, 1226-1241. PMID: 30108131

Note

For research use only.

图片

参考文献

产品说明书

Anti-GTPBP1 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GTPBP1 Polyclonal Antibody (HA399014)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Anti-GTPBP1 Polyclonal Antibody (HA399014)

概述

图片

参考文献

产品说明书

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