

| 货号 | HA413014 | ||||||||
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| 品牌 | abinScience | ||||||||
| 描述 |
Anti-Human NR2E1 Polyclonal Antibody (HA413014) is a rabbit polyclonal antibody detecting NR2E1 in WB, IHC, ELISA. Suitable for Human, Mouse, and Chicken.
Highlights
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| 种属反应性 | Human, Mouse | ||||||||
| 应用 | WB, IHC, ELISA | ||||||||
| 宿主 | Rabbit | ||||||||
| 同种型 | IgG | ||||||||
| 克隆类型 | Polyclonal | ||||||||
| 免疫原 | E. coli - derived recombinant Human NR2E1 (Met175-Ile385). | ||||||||
| 靶标 | NR2E1 | ||||||||
| 内毒素水平 | Please contact with the lab for this information. | ||||||||
| 纯化方式 | Purified by antigen affinity column. | ||||||||
| Accession号 | Q9Y466 | ||||||||
| 状态 | Liquid | ||||||||
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| 产品使用信息 |
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| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 别名 | Nuclear receptor subfamily 2 group E member 1, Nuclear receptor TLX, Protein tailless homolog, Tll, hTll, NR2E1 | ||||||||
| 背景 | Nuclear receptor subfamily 2 group E member 1 (NR2E1) is a ~42 kDa protein. Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required to pattern anterior brain differentiation. Involved in the regulation of retinal development and essential for vision. During retinogenesis, regulates PTEN-Cyclin D expression via binding to the promoter region of PTEN and suppressing its activity. May be involved in retinoic acid receptor (RAR) regulation in retinal cells. | ||||||||
| Note | For research use only. |

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