Anti-Human CAMLG Polyclonal Antibody (HW596014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HW596014

品牌

abinScience

描述

Anti-Human CAMLG Polyclonal Antibody (HW596014) is a rabbit polyclonal antibody detecting CAMLG in ELISA, IHC, WB. Suitable for Mus musculus and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human CAMLG (Gly19-Glu184).

靶标

CAMLG

纯化方式

Purified by antigen affinity column.

Accession号

P49069

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Guided entry of tail-anchored proteins factor CAMLG, Calcium signal-modulating cyclophilin ligand, CAMLG, CAML, GET2

背景

Guided entry of tail-anchored proteins factor CAMLG is a ~32 kDa protein. Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1/WRB, acts as a membrane receptor for soluble GET3/TRC40, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. Required for the stability of GET1. Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium. Essential for the survival of peripheral follicular B cells.

1. Yamamoto, Y. et al. (2012) Molecular cell 48, 387-97. PMID: 23041287

2. Vilardi, F. et al. (2014) PloS one 9, e85033. PMID: 24392163

3. Colombo, SF. et al. (2016) The Journal of biological chemistry 291, 15292-306. PMID: 27226539

4. Inglis, AJ. et al. (2020) Cell reports 30, 3691-3698.e5. PMID: 32187542

5. Bram, RJ. et al. (1994) Nature 371, 355-8. PMID: 7522304

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-CAMLG polyclonal antibody at 1ug/mL on various samples.
Lane 1: Jurkat cell lysate
Lane 2: 293T cell lysate
Lane 3: Mouse testis lysate
Lane 4: Mouse brain lysate

参考文献

产品说明书

Anti-Human CAMLG Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CAMLG Polyclonal Antibody (HW596014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human CAMLG Polyclonal Antibody (HW596014)

概述

图片

参考文献

产品说明书

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