Anti-Human TSC22D3 Polyclonal Antibody (HV509014)

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规格：

50ug
100ug

数量：

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概述
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参考文献
产品说明书

概述

货号

HV509014

品牌

abinScience

描述

Anti-Human TSC22D3 Polyclonal Antibody (HV509014) is a rabbit polyclonal antibody detecting TSC22D3 in ELISA, IHC, WB. Suitable for Rattus norvegicus, Macaca fascicularis, Mus musculus, Human, and Sus scrofa.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

种属反应性

Human, Mouse, Rat

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human TSC22D3 (Met1-Val134).

靶标

TSC22D3

纯化方式

Purified by antigen affinity column.

Accession号

Q99576

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

TSC22 domain family protein 3, DSIP-immunoreactive peptide, Protein DIP, hDIP, Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein, GILZ, TSC-22-like protein, TSC-22-related protein, TSC-22R, TSC22D3, DSIPI, GILZ

背景

TSC22 domain family protein 3 (TSC22D3) is a ~14 kDa protein. Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation and thereby NFKB1 DNA-binding activities. In vitro, suppresses AP-1 transcription factor complex DNA-binding activities.

1. Asselin-Labat, ML. et al. (2004) Blood 104, 215-23. PMID: 15031210

2. Berrebi, D. et al. (2003) Blood 101, 729-38. PMID: 12393603

3. Ayroldi, E. et al. (2001) Blood 98, 743-53. PMID: 11468175

Note

For research use only.

图片

参考文献

产品说明书

Anti-Human TSC22D3 Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSC22D3 Polyclonal Antibody (HV509014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human TSC22D3 Polyclonal Antibody (HV509014)

概述

图片

参考文献

产品说明书

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