Anti-Human BAZ1A Polyclonal Antibody (HA499014)

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50ug
100ug

数量：

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概述
图片
参考文献
产品说明书

概述

货号

HA499014

品牌

abinScience

描述

Anti-Human BAZ1A Polyclonal Antibody (HA499014) is a rabbit polyclonal antibody detecting BAZ1A in ELISA, IHC, WB. Suitable for Mus musculus and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

种属反应性

Human, Mouse

应用

ELISA, IHC, WB

宿主

Rabbit

克隆类型

Polyclonal

同种型

IgG

免疫原

E. coli - derived recombinant Human BAZ1A (Leu549-Arg666).

靶标

BAZ1A

纯化方式

Purified by antigen affinity column.

Accession号

Q9NRL2

状态

Liquid

保存溶液

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

别名

Bromodomain adjacent to zinc finger domain protein 1A, ATP-dependent chromatin-remodeling protein, ATP-utilizing chromatin assembly and remodeling factor 1, hACF1, CHRAC subunit ACF1, Williams syndrome transcription factor-related chromatin-remodeling factor 180, WCRF180, hWALp1, BAZ1A, ACF1, WCRF180, HSPC317

背景

Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) is a ~178 kDa protein. Regulatory subunit of the ATP-dependent ACF-1 and ACF-5 ISWI chromatin remodeling complexes, which form ordered nucleosome arrays on chromatin and slide edge- and center-positioned histone octamers away from their original location on the DNA template to facilitate access to DNA during DNA-templated processes such as DNA replication, transcription, and repair. Both complexes regulate the spacing of nucleosomes along the chromatin and have the ability to slide mononucleosomes to the center of a DNA template in an ATP-dependent manner. The ACF-1 ISWI chromatin remodeling complex has a lower ATP hydrolysis rate than the ACF-5 ISWI chromatin remodeling complex. Has a role in sensing the length of DNA which flank nucleosomes, which modulates the nucleosome spacing activity of the ACF-5 ISWI chromatin remodeling complex. Involved in DNA replication and together with SMARCA5/SNF2H is required for replication of pericentric heterochromatin in S-phase.

1. Yang, JG. et al. (2006) Nature structural & molecular biology 13, 1078-83. PMID: 17099699

2. Oppikofer, M. et al. (2017) EMBO reports 18, 1697-1706. PMID: 28801535

3. Kukimoto, I. et al. (2004) Molecular cell 13, 265-77. PMID: 14759371

4. Collins, N. et al. (2002) Nature genetics 32, 627-32. PMID: 12434153

5. Ewing, AK. et al. (2007) Molecular endocrinology (Baltimore, Md.) 21, 1791-806. PMID: 17519354

Note

For research use only.

图片

Western blot

Western blot analysis was performed using anti-BAZ1A polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate

参考文献

产品说明书

Anti-Human BAZ1A Polyclonal Antibody.pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BAZ1A Polyclonal Antibody (HA499014)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human BAZ1A Polyclonal Antibody (HA499014)

概述

图片

参考文献

产品说明书

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