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Anti-Human PYCR1 Polyclonal Antibody (HW791014)

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概述
货号HW791014
品牌abinScience
描述
Anti-Human PYCR1 Polyclonal Antibody (HW791014) is a rabbit polyclonal antibody detecting PYCR1 in ELISA, IHC, WB. Suitable for Bovine, Mus musculus, and Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human PYCR1 (Met1-Asp319).
靶标PYCR1
纯化方式Purified by antigen affinity column.
Accession号P32322
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息
应用方法 稀释比例
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Pyrroline-5-carboxylate reductase 1, mitochondrial, P5C reductase 1, P5CR 1, 1.5.1.2, PYCR1
背景

Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) is a ~33 kDa protein. Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in the cellular response to oxidative stress.

1. Meng, Z. et al. (2006) Journal of molecular biology 359, 1364-77. PMID: 16730026
2. Reversade, B. et al. (2009) Nature genetics 41, 1016-21. PMID: 19648921
3. De Ingeniis, J. et al. (2012) PloS one 7, e45190. PMID: 23024808
4. Christensen, EM. et al. (2017) The Journal of biological chemistry 292, 7233-7243. PMID: 28258219
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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