| 货号 | VK425014 |
|---|---|
| 品牌 | abinScience |
| 应用 | WB, IHC, ELISA |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 种属 | Chikungunya virus (strain S27-African prototype) (CHIKV) |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant CHIKV Spike glycoprotein E1 (Tyr810-Lys1221). |
| 经测试应用 | WB, ELISA |
| 靶标 | CHIKV-E1 |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q8JUX5 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Structural polyprotein, p130, Capsid protein, 3.4.21.90, Coat protein, C, Precursor of protein E3/E2, p62, pE2, Assembly protein E3, Spike glycoprotein E2, E2 envelope glycoprotein, 6K protein, Spike glycoprotein E1, E1 envelope glycoprotein |
| 背景 | Chikungunya virus (CHIKV) is a mosquito-borne alphavirus responsible for Chikungunya fever, a disease marked by fever, rash, and joint pain. The E1 envelope glycoprotein, a 47 kDa class II fusion protein, plays a critical role in viral entry by mediating low pH-triggered membrane fusion within host endosomes. It forms heterodimers with E2 glycoproteins, assembling into spike trimers on the viral surface that facilitate host cell attachment and infection. Due to its essential function in viral infectivity, the E1 protein is widely used in studies of viral entry, antibody development, vaccine design, and diagnostic assay optimization. |
| Note | For research use only. |
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