Anti-Human Dkk-1 Recombinant Antibody (SAA1268) (HF914033)

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50ug
100ug
1mg

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概述
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参考文献
产品说明书

HF914033

abinScience

种属反应性

Human

ELISA

VHH-hFc

SAA1268

Dickkopf-1, SK, hDkk-1, Dkk-1, Dickkopf-related protein 1, DKK1

内毒素水平

Please contact with the lab for this information.

>90% as determined by SDS-PAGE.

Protein A/G purified from cell culture supernatant.

Accession号

O94907

Anti-Human DKK1 Antibody (SAA1268) (abinScience Cat# HF914033, RRID:AB_3729854)

Liquid

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

产品使用信息

应用方法	稀释比例
ELISA	1:2000-1:20000

稳定性和存储

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Dickkopf-related protein 1 (DKK1) is a ~28 kDa protein. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity.

1. Ahn, VE. et al. (2011) Developmental cell 21, 862-73. PMID: 22000856

2. Niehrs, C. (2006) Oncogene 25, 7469-81. PMID: 17143291

For research use only.

Isotype Control

VHH-hFc (IgG1) Isotype Control antibody (cAb-Lys2) (ZP167307)

SDS-PAGE

SDS-PAGE for Anti-Human DKK1 Antibody (SAA1268)
Bioactivity

Detects recombinant human DKK1 (Catalog No: HF914011) in indirect ELISA

产品说明书

Anti-Human Dkk-1 Recombinant Antibody (SAA1268).pdf

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

分子量 *

g/mol

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

C₁ (起始浓度)

V₁ (起始体积)

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Dkk-1 Recombinant Antibody (SAA1268) (HF914033)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Anti-Human Dkk-1 Recombinant Antibody (SAA1268) (HF914033)

概述

图片

参考文献

产品说明书

相关产品推荐

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