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Anti-AQP9 Polyclonal Antibody (PTX19455)

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概述
货号PTX19455
品牌ProteoGenix
描述
Anti-AQP9 Polyclonal Antibody (PTX19455) is a rabbit polyclonal antibody detecting AQP-9,SSC1,Small solute channel 1,Aquaporin-9,AQP9,Aquaglyceroporin-9 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human AQP9 (Tyr125-Leu158).
靶标AQP-9,SSC1,Small solute channel 1,Aquaporin-9,AQP9,Aquaglyceroporin-9
纯化方式Purified by antigen affinity column.
Accession号O43315
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Aquaporin-9 (AQP9) is a ~31 kDa protein. Aquaglyceroporins form homotetrameric transmembrane channels, with each monomer independently mediating glycerol and water transport across the plasma membrane along their osmotic gradient. AQP9 is the primary route for glycerol uptake in hepatocytes, supporting hepatic gluconeogenesis. It exhibits broad specificity and may transport various small, non-charged solutes, including carbamides, polyols, purines, and pyrimidines. AQP9 may also facilitate hepatic urea extrusion. Due to its permeability to lactate, AQP9 might participate in the astrocyte-to-neuron lactate shuttle, supplying neurons with energy.

1. Tsukaguchi, H. et al. (1999) The American journal of physiology 277, F685-96. PMID: 10564231
2. Gotfryd, K. et al. (2018) Nature communications 9, 4749. PMID: 30420639
3. Geistlinger, K. et al. (2022) Life (Basel, Switzerland) 12. PMID: 35054513
4. Ishibashi, K. et al. (1998) Biochemical and biophysical research communications 244, 268-74. PMID: 9514918
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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