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Anti-Osteocalcin/BGLAP/OC Polyclonal Antibody (PTX18654)

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概述
货号PTX18654
品牌ProteoGenix
描述
Anti-Osteocalcin/BGLAP/OC Polyclonal Antibody (PTX18654) is a rabbit polyclonal antibody detecting Gamma-carboxyglutamic acid-containing protein,BGLAP,BGP,Bone Gla protein,Osteocalcin in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human Osteocalcin/BGLAP/OC (Lys24-Val100).
靶标Gamma-carboxyglutamic acid-containing protein,BGLAP,BGP,Bone Gla protein,Osteocalcin
纯化方式Purified by antigen affinity column.
Accession号P02818
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Osteocalcin (BGLAP) is a ~10 kDa protein. The carboxylated form is one of the main organic components of the bone matrix, which constitutes 1-2% of the total bone protein. Acts as a negative regulator of bone formation and is required to limit bone formation without impairing bone resorption or mineralization. Binds strongly to apatite and calcium upon gamma-carboxylation; this modification is essential for bone metabolism.

1. Celeste, AJ. et al. (1986) The EMBO journal 5, 1885-90. PMID: 3019668
2. Poser, JW. et al. (1980) The Journal of biological chemistry 255, 8685-91. PMID: 6967872
3. Wang, R. et al. (2025) Nature 639, 808-815. PMID: 39880952
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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