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Anti-BMP3/Osteogenin Polyclonal Antibody (PTX18483)

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概述
货号PTX18483
品牌ProteoGenix
描述
Anti-BMP3/Osteogenin Polyclonal Antibody (PTX18483) is a rabbit polyclonal antibody detecting BMP-3,Bone morphogenetic protein 3A,Osteogenin,BMP-3A,Bone morphogenetic protein 3,BMP3,BMP3A in ELISA, IHC, WB. Suitable for Human, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human BMP3/Osteogenin (Gln363-Arg472).
靶标BMP-3,Bone morphogenetic protein 3A,Osteogenin,BMP-3A,Bone morphogenetic protein 3,BMP3,BMP3A
纯化方式Purified by antigen affinity column.
Accession号P12645
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Bone morphogenetic protein 3 (BMP3/Osteogenin) is a ~53 kDa protein. Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentiation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways.

1. Daluiski, A. et al. (2001) Nature genetics 27, 84-8. PMID: 11138004
2. Kang, Q. et al. (2004) Gene therapy 11, 1312-20. PMID: 15269709
3. Wen, J. et al. (2019) Journal of experimental & clinical cancer research : CR 38, 428. PMID: 31665064
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-BMP3/Osteogenin Polyclonal Antibody

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