首页 > 产品中心 > 抗体 > 一抗

Anti-SMPD1 Polyclonal Antibody (PTX19602)

价格:
规格:
数量:
  • 概述

  • 图片

  • 参考文献

概述
货号PTX19602
品牌ProteoGenix
描述
Anti-SMPD1 Polyclonal Antibody (PTX19602) is a rabbit polyclonal antibody detecting aSMase,SMPD1,Acid sphingomyelinase,Sphingomyelin phosphodiesterase,ASM in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SMPD1 (Gly319-Gly579).
靶标aSMase,SMPD1,Acid sphingomyelinase,Sphingomyelin phosphodiesterase,ASM
纯化方式Purified by antigen affinity column.
Accession号P17405
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sphingomyelin phosphodiesterase (SMPD1) is a ~69 kDa protein. Converts sphingomyelin to ceramide. Exists as two enzymatic forms that arise from alternative trafficking of a single protein precursor, one that is targeted to the endolysosomal compartment, whereas the other is released extracellularly. However, in response to various forms of stress, lysosomal exocytosis may represent a major source of the secretory form.

1. Grassmé, H. et al. (2003) Nature medicine 9, 322-30. PMID: 12563314
2. Schuchman, EH. et al. (1991) The Journal of biological chemistry 266, 8531-9. PMID: 1840600
3. Jones, I. et al. (2008) Molecular genetics and metabolism 95, 152-62. PMID: 18815062
4. Oninla, VO. et al. (2014) Journal of lipid research 55, 2606-19. PMID: 25339683
5. Acuña, M. et al. (2016) European journal of human genetics : EJHG 24, 208-13. PMID: 25920558
6. Acuña, M. et al. (2016) Biochemical and biophysical research communications 479, 496-501. PMID: 27659707
7. Carpinteiro, A. et al. (2020) Cell reports. Medicine 1, 100142. PMID: 33163980
8. Jenkins, RW. et al. (2010) The Journal of biological chemistry 285, 35706-18. PMID: 20807762
9. Jenkins, RW. et al. (2011) The Journal of biological chemistry 286, 3777-88. PMID: 21098024
10. Schissel, SL. et al. (1998) The Journal of biological chemistry 273, 18250-9. PMID: 9660788
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐