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Anti-CD105/ENG Polyclonal Antibody (PTX19604)

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概述
货号PTX19604
品牌ProteoGenix
描述
Anti-CD105/ENG Polyclonal Antibody (PTX19604) is a rabbit polyclonal antibody detecting CD105,END,Endoglin,ENG in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CD105/ENG (Thr27-Gly581).
靶标CD105,END,Endoglin,ENG
纯化方式Purified by antigen affinity column.
Accession号P17813
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Endoglin (CD105/ENG) is a ~70 kDa protein. Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.

1. Castonguay, R. et al. (2011) The Journal of biological chemistry 286, 30034-46. PMID: 21737454
2. Nolan-Stevaux, O. et al. (2012) PloS one 7, e50920. PMID: 23300529
3. McAllister, KA. et al. (1994) Nature genetics 8, 345-51. PMID: 7894484
4. Lee, NY. et al. (2007) The Journal of biological chemistry 282, 21507-17. PMID: 17540773
5. Gougos, A. et al. (1990) The Journal of biological chemistry 265, 8361-4. PMID: 1692830
6. Alt, A. et al. (2012) PloS one 7, e29948. PMID: 22347366
7. Bellón, T. et al. (1993) European journal of immunology 23, 2340-5. PMID: 8370410
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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