

| 货号 | PTX19617 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CD72 Polyclonal Antibody (PTX19617) is a rabbit polyclonal antibody detecting CD72,Lyb-2,B-cell differentiation antigen CD72 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CD72 (Glu169-Asp359). |
| 靶标 | CD72,Lyb-2,B-cell differentiation antigen CD72 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P21854 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | B-cell differentiation antigen CD72 is a ~40 kDa protein. Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis. |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理