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Anti-AQP1 Polyclonal Antibody (PTX19651)

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概述
货号PTX19651
品牌ProteoGenix
描述
Anti-AQP1 Polyclonal Antibody (PTX19651) is a rabbit polyclonal antibody detecting Aquaporin-CHIP,Urine water channel,AQP-1,Aquaporin-1,AQP1,CHIP28,Water channel protein for red blood cells and kidney proximal tubule in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human AQP1 (Val201-Lys269).
靶标Aquaporin-CHIP,Urine water channel,AQP-1,Aquaporin-1,AQP1,CHIP28,Water channel protein for red blood cells and kidney proximal tubule
纯化方式Purified by antigen affinity column.
Accession号P29972
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Aquaporin-1 (AQP1) is a ~28 kDa protein. Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues. Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol. In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo.

1. Preston, GM. et al. (1992) Science (New York, N.Y.) 256, 385-7. PMID: 1373524
2. Rungaldier, S. et al. (2013) Biochimica et biophysica acta 1828, 956-66. PMID: 23219802
3. Herrera, M. et al. (2006) Hypertension (Dallas, Tex. : 1979) 48, 157-64. PMID: 16682607
4. Endeward, V. et al. (2006) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20, 1974-81. PMID: 17012249
5. Musa-Aziz, R. et al. (2009) Proceedings of the National Academy of Sciences of the United States of America 106, 5406-11. PMID: 19273840
6. Montiel, V. et al. (2020) Science translational medicine 12. PMID: 33028705
7. Abrami, L. et al. (1996) Pflugers Archiv : European journal of physiology 431, 408-14. PMID: 8584435
8. Vallese, F. et al. (2022) Nature structural & molecular biology 29, 706-718. PMID: 35835865
9. Henderson, SW. et al. (2023) Biophysical reports 3, 100100. PMID: 36949749
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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