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Anti-CD144/CDH5 Polyclonal Antibody (PTX19669)

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概述
货号PTX19669
品牌ProteoGenix
描述
Anti-CD144/CDH5 Polyclonal Antibody (PTX19669) is a rabbit polyclonal antibody detecting 7B4 antigen,CD144,VE-cadherin,Cadherin-5,CDH5,Vascular endothelial cadherin in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CD144/CDH5 (Val68-Thr307).
靶标7B4 antigen,CD144,VE-cadherin,Cadherin-5,CDH5,Vascular endothelial cadherin
纯化方式Purified by antigen affinity column.
Accession号P33151
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cadherin-5 (CD144/CDH5) is a ~87 kDa protein. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play a important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. It associates with alpha-catenin forming a link to the cytoskeleton. Plays a role in coupling actin fibers to cell junctions in endothelial cells, via acting as a cell junctional complex anchor for AMOTL2 and MAGI1.

1. Brasch, J. et al. (2011) Journal of molecular biology 408, 57-73. PMID: 21269602
2. Shimoyama, Y. et al. (2000) The Biochemical journal 349, 159-67. PMID: 10861224
3. Lampugnani, MG. et al. (2010) Journal of cell science 123, 1073-80. PMID: 20332120
4. Abiko, H. et al. (2015) Journal of cell science 128, 1683-95. PMID: 25795300
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-CD144/CDH5 Polyclonal Antibody

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