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Anti-HSPA1L Polyclonal Antibody (PTX18591)

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概述
货号PTX18591
品牌ProteoGenix
描述
Anti-HSPA1L Polyclonal Antibody (PTX18591) is a rabbit polyclonal antibody detecting HSP70-Hom,Heat shock 70 kDa protein 1L,Heat shock 70 kDa protein 1-like,HSPA1L,Heat shock 70 kDa protein 1-Hom in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human HSPA1L (Met1-Asp641).
靶标HSP70-Hom,Heat shock 70 kDa protein 1L,Heat shock 70 kDa protein 1-like,HSPA1L,Heat shock 70 kDa protein 1-Hom
纯化方式Purified by antigen affinity column.
Accession号P34931
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Heat shock 70 kDa protein 1-like (HSPA1L) is a ~70 kDa protein. Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP release, mediated by co-chaperones. The affinity for polypeptides is regulated by its nucleotide bound state. In the ATP-bound form, it has a low affinity for substrate proteins.

1. Radons, J. (2016) Cell stress & chaperones 21, 379-404. PMID: 26865365
2. Hasson, SA. et al. (2013) Nature 504, 291-5. PMID: 24270810
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-HSPA1L Polyclonal Antibody

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