

| 货号 | PTX19683 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-FDFT1 Polyclonal Antibody (PTX19683) is a rabbit polyclonal antibody detecting Squalene synthase, Farnesyl-diphosphate farnesyltransferase 1, FDFT1, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human FDFT1 (Met1-Gln283). |
| 靶标 | Squalene synthase, Farnesyl-diphosphate farnesyltransferase 1, FDFT1, SQS, SS, FPP:FPP farnesyltransferase, Farnesyl-diphosphate farnesyltransferase |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P37268 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Squalene synthase (FDFT1) is a ~48 kDa protein. Catalyzes the condensation of 2 farnesyl pyrophosphate (FPP) moieties to form squalene. Proceeds in two distinct steps. In the first half-reaction, two molecules of FPP react to form the stable presqualene diphosphate intermediate (PSQPP), with concomitant release of a proton and a molecule of inorganic diphosphate. In the second half-reaction, PSQPP undergoes heterolysis, isomerization, and reduction with NADPH or NADH to form squalene. It is the first committed enzyme of the sterol biosynthesis pathway. |
| Note | For research use only. |

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