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Anti-CASP2 Polyclonal Antibody (PTX19695)

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概述
货号PTX19695
品牌ProteoGenix
描述
Anti-CASP2 Polyclonal Antibody (PTX19695) is a rabbit polyclonal antibody detecting Protease ICH-1,ICH1,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD2,CASP-2,Caspase-2,CASP2,NEDD-2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CASP2 (Gly334-Thr452).
靶标Protease ICH-1,ICH1,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD2,CASP-2,Caspase-2,CASP2,NEDD-2
纯化方式Purified by antigen affinity column.
Accession号P42575
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Caspase-2 (CASP2) is a ~50 kDa protein. Is a regulator of the cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.

1. Droin, N. et al. (2000) Cancer research 60, 7039-47. PMID: 11156409
2. Tinel, A. et al. (2004) Science (New York, N.Y.) 304, 843-6. PMID: 15073321
3. Wang, L. et al. (1994) Cell 78, 739-50. PMID: 8087842
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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