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Anti-ABCG1 Polyclonal Antibody (PTX19704)

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概述
货号PTX19704
品牌ProteoGenix
描述
Anti-ABCG1 Polyclonal Antibody (PTX19704) is a rabbit polyclonal antibody detecting ATP-binding cassette transporter 8,ABC8,ATP-binding cassette sub-family G member 1,ABCG1,WHT1,White protein homolog in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human ABCG1 (Met1-His353).
靶标ATP-binding cassette transporter 8,ABC8,ATP-binding cassette sub-family G member 1,ABCG1,WHT1,White protein homolog
纯化方式Purified by antigen affinity column.
Accession号P45844
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

ATP-binding cassette sub-family G member 1 (ABCG1) is a ~75 kDa protein. Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP. The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages.

1. Engel, T. et al. (2007) FEBS letters 581, 1673-80. PMID: 17408620
2. Gu, HM. et al. (2014) Biochimica et biophysica acta 1841, 847-58. PMID: 24576892
3. Kobayashi, A. et al. (2006) Journal of lipid research 47, 1791-802. PMID: 16702602
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-ABCG1 Polyclonal Antibody

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