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Anti-CDKN1B Polyclonal Antibody (PTX18532)

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概述
货号PTX18532
品牌ProteoGenix
描述
Anti-CDKN1B Polyclonal Antibody (PTX18532) is a rabbit polyclonal antibody detecting Cyclin-dependent kinase inhibitor 1B,KIP1,CDKN1B,p27Kip1,Cyclin-dependent kinase inhibitor p27 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CDKN1B (Met1-Thr198).
靶标Cyclin-dependent kinase inhibitor 1B,KIP1,CDKN1B,p27Kip1,Cyclin-dependent kinase inhibitor p27
纯化方式Purified by antigen affinity column.
Accession号P46527
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Cyclin-dependent kinase inhibitor 1B (CDKN1B) is a ~22 kDa protein. Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA. Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation.

1. McGrath, DA. et al. (2017) The EMBO journal 36, 2251-2262. PMID: 28666995
NoteFor research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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