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Anti-CD183/CXCR3 Polyclonal Antibody (PTX19714)

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概述
货号PTX19714
品牌ProteoGenix
描述
Anti-CD183/CXCR3 Polyclonal Antibody (PTX19714) is a rabbit polyclonal antibody detecting CXCR3,G protein-coupled receptor 9,CXC-R3,Interferon-inducible protein 10 receptor,IP-10 receptor,C-X-C chemokine receptor type 3,GPR9,CD183,CKR-L2,CXCR-3 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CD183/CXCR3 (Met1-Arg53).
靶标CXCR3,G protein-coupled receptor 9,CXC-R3,Interferon-inducible protein 10 receptor,IP-10 receptor,C-X-C chemokine receptor type 3,GPR9,CD183,CKR-L2,CXCR-3
纯化方式Purified by antigen affinity column.
Accession号P49682
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

C-X-C chemokine receptor type 3 (CD183/CXCR3) is a ~40 kDa protein. Receptor for the C-X-C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G-protein signaling pathway. Binds to CCL21. Probably promotes cell chemotaxis response. Upon activation by PF4, induces activated T-lymphocytes migration mediated via downstream Ras/extracellular signal-regulated kinase (ERK) signaling.

1. Lasagni, L. et al. (2003) The Journal of experimental medicine 197, 1537-49. PMID: 12782716
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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Anti-CD183/CXCR3 Polyclonal Antibody

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