

| 货号 | PTX18559 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-EBI3/IL27B Polyclonal Antibody (PTX18559) is a rabbit polyclonal antibody detecting IL-27B,Interleukin-27 subunit beta,EBI3,Epstein-Barr virus-induced gene 3 protein,EBV-induced gene 3 protein,IL27B,IL-27 subunit beta in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human EBI3/IL27B (Arg21-Lys229). |
| 靶标 | IL-27B,Interleukin-27 subunit beta,EBI3,Epstein-Barr virus-induced gene 3 protein,EBV-induced gene 3 protein,IL27B,IL-27 subunit beta |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q14213 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Interleukin-27 subunit beta (EBI3/IL27B) is a ~25 kDa protein. Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. |
| Note | For research use only. |

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