

| 货号 | PTX19820 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CASP10 Polyclonal Antibody (PTX19820) is a rabbit polyclonal antibody detecting FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,CASP-10,MCH4,ICE-like apoptotic protease 4,Apoptotic protease Mch-4,CASP10,Caspase-10 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human CASP10 (Phe223-Ile459). |
| 靶标 | FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,CASP-10,MCH4,ICE-like apoptotic protease 4,Apoptotic protease Mch-4,CASP10,Caspase-10 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q92851 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Caspase-10 (CASP10) is a ~58 kDa protein. Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates effector caspases CASP3, CASP4, CASP6, CASP7, CASP8 and CASP9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. |
| Note | For research use only. |

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