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Anti-MGLL Polyclonal Antibody (PTX19835)

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概述
货号PTX19835
品牌ProteoGenix
描述
Anti-MGLL Polyclonal Antibody (PTX19835) is a rabbit polyclonal antibody detecting Lysophospholipase-like,MGLL,Monoacylglycerol lipase,Lysophospholipase homolog,MGL,Monoglyceride lipase,HU-K5,MAGL in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human MGLL (Met1-Pro303).
靶标Lysophospholipase-like,MGLL,Monoacylglycerol lipase,Lysophospholipase homolog,MGL,Monoglyceride lipase,HU-K5,MAGL
纯化方式Purified by antigen affinity column.
Accession号Q99685
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.

1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917
2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333
3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984
4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151
5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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