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Anti-HDAC8 Polyclonal Antibody (PTX19839)

概述
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参考文献

概述

货号	PTX19839
品牌	ProteoGenix
描述	Anti-HDAC8 Polyclonal Antibody (PTX19839) is a rabbit polyclonal antibody detecting HDAC8,Histone deacetylase 8,HD8,HDACL1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat. Highlights Affinity Purified — Minimal background and high purity for reliable results. Multi-Application — Validated across multiple applications. Multi-Species — Cross-reactive for translational research.
种属反应性	Human, Mouse, Rat
应用	ELISA, IHC, WB
宿主	Rabbit
同种型	IgG
克隆类型	Polyclonal
免疫原	E. coli - derived recombinant Human HDAC8 (Met1-Val377).
靶标	HDAC8,Histone deacetylase 8,HD8,HDACL1
纯化方式	Purified by antigen affinity column.
Accession号	Q9BY41
状态	Liquid
保存溶液	0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Histone deacetylase 8 (HDAC8) is a ~41 kDa protein. Histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. 1. Hu, E. et al. (2000) The Journal of biological chemistry 275, 15254-64. PMID: 10748112 2. Van den Wyngaert, I. et al. (2000) FEBS letters 478, 77-83. PMID: 10922473 3. Buggy, JJ. et al. (2000) The Biochemical journal 350 Pt 1, 199-205. PMID: 10926844 4. Lee, H. et al. (2004) Molecular and cellular biology 24, 765-73. PMID: 14701748 5. Wei, W. et al. (2017) Cell research 27, 898-915. PMID: 28497810
Note	For research use only.

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参考文献

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

=

浓度

×

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

×

V₁ (起始体积)

=

工作液

C₂ (终浓度)

×

V₂ (终体积)

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Anti-HDAC8 Polyclonal Antibody

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