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Anti-PTGES2 Polyclonal Antibody (PTX19845)

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概述
货号PTX19845
品牌ProteoGenix
描述
Anti-PTGES2 Polyclonal Antibody (PTX19845) is a rabbit polyclonal antibody detecting Microsomal prostaglandin E synthase 2,PGES2,Membrane-associated prostaglandin E synthase-2,Prostaglandin E synthase 2,Prostaglandin-H(2) E-isomerase,C9orf15,mPGES-2,mPGE synthase-2,PTGES2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human PTGES2 (Tyr145-Thr357).
靶标Microsomal prostaglandin E synthase 2,PGES2,Membrane-associated prostaglandin E synthase-2,Prostaglandin E synthase 2,Prostaglandin-H(2) E-isomerase,C9orf15,mPGES-2,mPGE synthase-2,PTGES2
纯化方式Purified by antigen affinity column.
Accession号Q9H7Z7
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Prostaglandin E synthase 2 (PTGES2) is a ~41 kDa protein. Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).

1. Watanabe, K. et al. (2003) Biochemical and biophysical research communications 306, 577-81. PMID: 12804604
2. Yamada, T. et al. (2007) Biochemistry 46, 8414-24. PMID: 17585783
3. Watanabe, K. et al. (2008) Biochemical and biophysical research communications 367, 782-6. PMID: 18198127
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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