

| 货号 | PTX19846 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CD229/LY9 Polyclonal Antibody (PTX19846) is a rabbit polyclonal antibody detecting SLAM family member 3,Lymphocyte antigen 9,Cell surface molecule Ly-9,T-lymphocyte surface antigen Ly-9,Signaling lymphocytic activation molecule 3,CD229,LY9,SLAMF3 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human CD229/LY9 (Met161-Arg358). |
| 靶标 | SLAM family member 3,Lymphocyte antigen 9,Cell surface molecule Ly-9,T-lymphocyte surface antigen Ly-9,Signaling lymphocytic activation molecule 3,CD229,LY9,SLAMF3 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9HBG7 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | T-lymphocyte surface antigen Ly-9 (CD229/LY9) is a ~72 kDa protein. Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. May participate in adhesion reactions between T lymphocytes and accessory cells by homophilic interaction. Promotes T-cell differentiation into a helper T-cell Th17 phenotype leading to increased IL-17 secretion; the costimulatory activity requires SH2D1A. 1. Chatterjee, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 188, 1206-12. PMID: 22184727 2. Chatterjee, M. et al. (2012) The Journal of biological chemistry 287, 38168-77. PMID: 22989874 |
| Note | For research use only. |

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