

| 货号 | PTX18539 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CNOT6 Polyclonal Antibody (PTX18539) is a rabbit polyclonal antibody detecting KIAA1194,CCR4,CNOT6,CCR4a,CCR4 carbon catabolite repression 4-like,Cytoplasmic deadenylase,Carbon catabolite repressor protein 4 homolog,CCR4-NOT transcription complex subunit 6 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CNOT6 (Leu153-Arg557). |
| 靶标 | KIAA1194,CCR4,CNOT6,CCR4a,CCR4 carbon catabolite repression 4-like,Cytoplasmic deadenylase,Carbon catabolite repressor protein 4 homolog,CCR4-NOT transcription complex subunit 6 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9ULM6 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | CCR4-NOT transcription complex subunit 6 (CNOT6) is a ~63 kDa protein. Poly(A) nuclease with 3'-5' RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. |
| Note | For research use only. |

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