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Anti-CILK1 Polyclonal Antibody (PTX19880)

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概述
货号PTX19880
品牌ProteoGenix
描述
Anti-CILK1 Polyclonal Antibody (PTX19880) is a rabbit polyclonal antibody detecting Ciliogenesis associated kinase 1,Serine/threonine-protein kinase ICK,MAK-related kinase,ICK,KIAA0936,hICK,Laryngeal cancer kinase 2,CILK1,MRK,LCK2,Intestinal cell kinase in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
种属反应性Human, Mouse, Rat
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human CILK1 (Met1-Gln277).
靶标Ciliogenesis associated kinase 1,Serine/threonine-protein kinase ICK,MAK-related kinase,ICK,KIAA0936,hICK,Laryngeal cancer kinase 2,CILK1,MRK,LCK2,Intestinal cell kinase
纯化方式Purified by antigen affinity column.
Accession号Q9UPZ9
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Serine/threonine-protein kinase ICK (CILK1) is a ~71 kDa protein. Required for ciliogenesis. Phosphorylates KIF3A. Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips. May play a key role in the development of multiple organ systems and particularly in cardiac development.

1. Chaya, T. et al. (2014) The EMBO journal 33, 1227-42. PMID: 24797473
2. Moon, H. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 8541-6. PMID: 24853502
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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