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Anti-CD218b/IL18RAP Polyclonal Antibody (PTX19894)

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概述
货号PTX19894
品牌ProteoGenix
描述
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
克隆类型Polyclonal
同种型IgG
免疫原E. coli - derived recombinant Human CD218b/IL18RAP (Phe20-Arg356).
靶标AcPL,Accessory protein-like,Interleukin-1 receptor 7,IL-18R-beta,CD218 antigen-like family member B,IL-1RAcPL,Interleukin-18 receptor accessory protein,CDw218b,IL-1R-7,IL1R7,IL-1R7,IL-18RAcP,CD218b,IL-1R accessory protein-like,IL18RAP,Interleukin-18 receptor accessory protein-like,IL-18 receptor accessory protein,IL-18Rbeta,Interleukin-18 receptor beta
纯化方式Purified by antigen affinity column.
Accession号O95256
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Interleukin-18 receptor accessory protein (CD218b/IL18RAP) is a ~68 kDa protein. Within the IL18 receptor complex, does not mediate IL18-binding, but involved in IL18-dependent signal transduction, leading to NF-kappa-B and JNK activation. May play a role in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (Probable).

1. Kato, Z. et al. (2003) Nature structural biology 10, 966-71. PMID: 14528293
2. Tsutsumi, N. et al. (2014) Nature communications 5, 5340. PMID: 25500532
3. Born, TL. et al. (1998) The Journal of biological chemistry 273, 29445-50. PMID: 9792649
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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