

| 货号 | PTX18538 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CLU Polyclonal Antibody (PTX18538) is a rabbit polyclonal antibody detecting APOJ,ApoJalpha,NA1/NA2,Complement cytolysis inhibitor,Complement cytolysis inhibitor a chain,Ku70-binding protein 1,Testosterone-repressed prostate message 2,ApoJbeta,TRPM-2,Complement cytolysis inhibitor b chain,SGP-2,KUB1,Apolipoprotein J,Apo-J,Clusterin,Sulfated glycoprotein 2,Aging-associated gene 4 protein,CLI,CLU,Complement-associated protein SP-40,40 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CLU (Ser228-Glu449). |
| 靶标 | APOJ,ApoJalpha,NA1/NA2,Complement cytolysis inhibitor,Complement cytolysis inhibitor a chain,Ku70-binding protein 1,Testosterone-repressed prostate message 2,ApoJbeta,TRPM-2,Complement cytolysis inhibitor b chain,SGP-2,KUB1,Apolipoprotein J,Apo-J,Clusterin,Sulfated glycoprotein 2,Aging-associated gene 4 protein,CLI,CLU,Complement-associated protein SP-40,40 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P10909 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Clusterin (APOJ/SP-40) is a ~52 kDa protein. Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro). Does not require ATP. Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70. 1. Poon, S. et al. (2000) Biochemistry 39, 15953-60. PMID: 11123922 2. Wyatt, AR. et al. (2009) The Journal of biological chemistry 284, 21920-21927. PMID: 19535339 3. Poon, S. et al. (2002) The Journal of biological chemistry 277, 39532-40. PMID: 12176985 4. Stewart, EM. et al. (2007) Biochemistry 46, 1412-22. PMID: 17260971 5. Wyatt, AR. et al. (2010) The Journal of biological chemistry 285, 3532-3539. PMID: 19996109 6. Hatters, DM. et al. (2002) European journal of biochemistry 269, 2789-94. PMID: 12047389 7. Kumita, JR. et al. (2007) Journal of molecular biology 369, 157-67. PMID: 17407782 8. Yerbury, JJ. et al. (2007) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 21, 2312-22. PMID: 17412999 |
| Note | For research use only. |

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