

| 货号 | PTX19898 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CD59 Polyclonal Antibody (PTX19898) is a rabbit polyclonal antibody detecting MSK21,MAC-inhibitory protein,MEM43 antigen,MAC-IP,MIN2,MIRL,HRF20,Protectin,1F5 antigen,MIC11,MIN3,Membrane inhibitor of reactive lysis,MACIF,20 kDa homologous restriction factor,CD59,MIN1,CD59 glycoprotein,HRF-20,Membrane attack complex inhibition factor in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CD59 (Leu26-Asn102). |
| 靶标 | MSK21,MAC-inhibitory protein,MEM43 antigen,MAC-IP,MIN2,MIRL,HRF20,Protectin,1F5 antigen,MIC11,MIN3,Membrane inhibitor of reactive lysis,MACIF,20 kDa homologous restriction factor,CD59,MIN1,CD59 glycoprotein,HRF-20,Membrane attack complex inhibition factor |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P13987 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | CD59 glycoprotein is a ~14 kDa protein. Potent inhibitor of the complement membrane attack complex (MAC) action, which protects human cells from damage during complement activation. Acts by binding to the beta-haipins of C8 (C8A and C8B) components of the assembling MAC, forming an intermolecular beta-sheet that prevents incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. 1. Farkas, I. et al. (2002) The Journal of physiology 539, 537-45. PMID: 11882685 2. Meri, S. et al. (1990) Immunology 71, 1-9. PMID: 1698710 3. Okada, H. et al. (1989) Biochemical and biophysical research communications 162, 1553-9. PMID: 2475111 4. Davies, A. et al. (1989) The Journal of experimental medicine 170, 637-54. PMID: 2475570 5. Sugita, Y. et al. (1989) Journal of biochemistry 106, 555-7. PMID: 2606909 6. Bodian, DL. et al. (1997) The Journal of experimental medicine 185, 507-16. PMID: 9053451 7. Couves, EC. et al. (2023) Nature communications 14, 890. PMID: 36797260 |
| Note | For research use only. |

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