

| 货号 | PTX19909 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CD178/FASLG/TNFSF6 Polyclonal Antibody (PTX19909) is a rabbit polyclonal antibody detecting Receptor-binding FasL ectodomain,APL,APT1LG1,FasL ICD,Fas antigen ligand,CD178,sFasL,CD95L,APTL,TNFSF6,Apoptosis antigen ligand,SPA,FASLG,FasL,SPPL2A-processed FasL form,Tumor necrosis factor ligand superfamily member 6,Soluble Fas ligand,Fas ligand,CD95 ligand,CD95-L,FASL in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human CD178/FASLG/TNFSF6 (Gln103-Leu281). |
| 靶标 | Receptor-binding FasL ectodomain,APL,APT1LG1,FasL ICD,Fas antigen ligand,CD178,sFasL,CD95L,APTL,TNFSF6,Apoptosis antigen ligand,SPA,FASLG,FasL,SPPL2A-processed FasL form,Tumor necrosis factor ligand superfamily member 6,Soluble Fas ligand,Fas ligand,CD95 ligand,CD95-L,FASL |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | P48023 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Tumor necrosis factor ligand superfamily member 6 (CD178/FASLG) is a ~31 kDa protein. Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. Involved in cytotoxic T-cell-mediated apoptosis, natural killer cell-mediated apoptosis and in T-cell development. Initiates fratricidal/suicidal activation-induced cell death (AICD) in antigen-activated T-cells contributing to the termination of immune responses. TNFRSF6/FAS-mediated apoptosis also has a role in the induction of peripheral tolerance. Binds to TNFRSF6B/DcR3, a decoy receptor that blocks apoptosis. 1. Ruiz-García, R. et al. (2015) Pediatric research 78, 603-8. PMID: 26334989 2. Schneider, P. et al. (1997) The Journal of biological chemistry 272, 18827-33. PMID: 9228058 3. Alderson, MR. et al. (1995) The Journal of experimental medicine 181, 71-7. PMID: 7528780 4. Tanaka, M. et al. (1998) Nature medicine 4, 31-6. PMID: 9427603 5. Liu, W. et al. (2016) Structure (London, England : 1993) 24, 2016-2023. PMID: 27806260 |
| Note | For research use only. |

24小时产品查询

扫一扫关注我们

专属渠道经理