

| 货号 | PTX19927 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-CD280/MRC2 Polyclonal Antibody (PTX19927) is a rabbit polyclonal antibody detecting Urokinase receptor-associated protein,MRC2,CD280,Endocytic receptor 180,KIAA0709,C-type lectin domain family 13 member E,CLEC13E,UPARAP,ENDO180,UPAR-associated protein,C-type mannose receptor 2,Macrophage mannose receptor 2,Urokinase-type plasminogen activator receptor-associated protein in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
| 种属反应性 | Human, Mouse, Rat |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 同种型 | IgG |
| 克隆类型 | Polyclonal |
| 免疫原 | E. coli - derived recombinant Human CD280/MRC2 (Pro41-Lys505). |
| 靶标 | Urokinase receptor-associated protein,MRC2,CD280,Endocytic receptor 180,KIAA0709,C-type lectin domain family 13 member E,CLEC13E,UPARAP,ENDO180,UPAR-associated protein,C-type mannose receptor 2,Macrophage mannose receptor 2,Urokinase-type plasminogen activator receptor-associated protein |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q9UBG0 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | C-type mannose receptor 2 (CD280/MRC2) is a ~166 kDa protein. May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. |
| Note | For research use only. |

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