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Anti-Obinutuzumab Polyclonal Antibody (PTX18871)

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概述
货号PTX18871
品牌ProteoGenix
描述
Anti-Obinutuzumab Polyclonal Antibody (PTX18871) is a rabbit polyclonal antibody detecting Rabbit polyclonal to Gazyva. in ELISA.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Validated for ELISA — Optimized for consistent performance.
应用ELISA
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原Obinutuzumab
靶标Rabbit polyclonal to Gazyva.
特异性The product is specific for Obinutuzumab. This antibody serves as an excellent positive control for Obinutuzumab immunogenicity (ADA) assays.
纯化方式Purified by antigen affinity column.
Accession号CAS: 949142-50-1
状态Liquid
保存溶液 0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

稳定性和存储The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
背景Obinutuzumab is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment. It was approved under the trade name Gazyva by the US FDA in 2013, and as Gazyvaro by the EMA in Europe, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients, and as a second line treatment for follicular lymphoma. Obinutuzumab is a fully humanized monoclonal antibody that binds to an epitope on CD20 that partially overlaps with the epitope recognized by rituximab. Obinutuzumab binds to CD20 on B cells and causes these cells to be destroyed by engaging the adaptive immune system, directly activating intracellular apoptosis pathways, and activating the complement system.
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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