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Anti-Avelumab Polyclonal Antibody (PTX18882)

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概述
货号PTX18882
品牌ProteoGenix
描述
Anti-Avelumab Polyclonal Antibody (PTX18882) is a rabbit polyclonal antibody detecting Rabbit polyclonal to Bavencio. in ELISA.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Validated for ELISA — Optimized for consistent performance.
应用ELISA
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原Avelumab
靶标Rabbit polyclonal to Bavencio.
特异性The product is specific for Avelumab. This antibody serves as an excellent positive control for Avelumab immunogenicity (ADA) assays.
纯化方式Purified by antigen affinity column.
Accession号CAS: 1537032-82-8
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
背景Avelumab with trade name Bavencio, is an FDA-approved drug to treat Merkel cell carcinoma, urothelial carcinoma, and renal cell carcinoma. Avelumab is a whole monoclonal antibody of isotype IgG1 that binds to the programmed death-ligand 1 (PD-L1) and therefore inhibits binding to its receptor programmed cell death 1 (PD-1). PD-L1 can be highly expressed on certain tumors, which is thought to lead to reduced activation of immune cells (cytotoxic T-cells in particular) that might otherwise recognize and attack the cancer. Inhibition of PD-L1 by Avelumab can remove this inhibitor effect and thereby engender an anti-tumor response. It is one of several ways to block inhibitory signals related to T-cell activation, a more general strategy known as
NoteAntibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
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参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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