

| 货号 | PTX20106 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human P2RX4 Polyclonal Antibody (PTX20106) is a rabbit polyclonal antibody detecting Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human P2RX4 (Gln55-Asn338). |
| 靶标 | Purinergic receptor, P2RX4, P2X4, P2X purinoceptor 4, ATP receptor |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | Q99571 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | P2X purinoceptor 4 (P2RX4) is a ~43 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and calcium. CTP, but not GTP or UTP, functions as a weak affinity agonist for P2RX4. Activated by extracellularly released ATP, it plays multiple role in immunity and central nervous system physiology. Plays a key role in initial steps of T-cell activation and Ca(2+) microdomain formation. Also participates in basal T-cell activity without TCR/CD3 stimulation. 1. Garcia-Guzman, M. et al. (1997) Molecular pharmacology 51, 109-18. PMID: 9016352 2. Hamoudi, C. et al. (2022) Journal of immunology (Baltimore, Md. : 1950) 208, 1115-1127. PMID: 35165166 |
| Note | For research use only. |

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