

| 货号 | PTX20115 |
|---|---|
| 品牌 | ProteoGenix |
| 描述 |
Anti-Human FXYD1 Polyclonal Antibody (PTX20115) is a rabbit polyclonal antibody detecting Sodium/potassium-transporting ATPase subunit FXYD1, PLM, FXYD1, Phospholemman, FXYD domain-containing ion transport regulator 1 in ELISA, IHC, WB. Suitable for Human.
Highlights
|
| 种属反应性 | Human |
| 应用 | ELISA, IHC, WB |
| 宿主 | Rabbit |
| 克隆类型 | Polyclonal |
| 同种型 | IgG |
| 免疫原 | E. coli - derived recombinant Human FXYD1 (Glu21-Arg92). |
| 靶标 | Sodium/potassium-transporting ATPase subunit FXYD1, PLM, FXYD1, Phospholemman, FXYD domain-containing ion transport regulator 1 |
| 纯化方式 | Purified by antigen affinity column. |
| Accession号 | O00168 |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Phospholemman (FXYD1) is a ~10 kDa protein. Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell. Inhibits NKA activity in its unphosphorylated state and stimulates activity when phosphorylated. Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Contributes to female sexual development by maintaining the excitability of neurons which secrete gonadotropin-releasing hormone. |
| Note | For research use only. |

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