注册
CN
首页 > 产品中心 > 抗体 > 一抗

Anti-Human SPHK2 Polyclonal Antibody (PTX20119)

价格:
规格：
数量：
联系我们
一键复制产品信息

  • 概述

  • 图片

  • 参考文献

概述
货号PTX20119
品牌ProteoGenix
描述
Anti-Human SPHK2 Polyclonal Antibody (PTX20119) is a rabbit polyclonal antibody detecting SK2, Sphingosine kinase 2, SPHK2, SK 2, SPK 2 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human SPHK2 (Gly170-His370).
靶标SK2, Sphingosine kinase 2, SPHK2, SK 2, SPK 2
纯化方式Purified by antigen affinity column.
Accession号Q9NRA0
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Sphingosine kinase 2 (SPHK2) is a ~69 kDa protein. Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. In contrast to prosurvival SPHK1, has a positive effect on intracellular ceramide levels, inhibits cells growth and enhances apoptosis. In mitochondria, is important for cytochrome-c oxidase assembly and mitochondrial respiration.

1. Igarashi, N. et al. (2003) The Journal of biological chemistry 278, 46832-9. PMID: 12954646
2. Don, AS. et al. (2009) Biochemical and biophysical research communications 380, 87-92. PMID: 19168031
3. Maceyka, M. et al. (2005) The Journal of biological chemistry 280, 37118-29. PMID: 16118219
4. Strub, GM. et al. (2011) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25, 600-12. PMID: 20959514
5. Hait, NC. et al. (2009) Science (New York, N.Y.) 325, 1254-7. PMID: 19729656
6. Okada, T. et al. (2005) The Journal of biological chemistry 280, 36318-25. PMID: 16103110
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

相关产品推荐

获取报价

Anti-Human SPHK2 Polyclonal Antibody

  • 7X24小时产品咨询热线：027--87433958(9:00-18:00)，或扫描下方产品专员二维码或在线留言

  • 武汉东湖新技术开发区神墩四路666号研发楼B区3层东

  • 24小时产品查询

    24小时产品查询

  • 24小时产品查询

    扫一扫关注我们

  • 24小时产品查询

    专属渠道经理

Copyright © 2026 武汉艾必赛生物科技有限公司版权所有 所有产品仅可用于工业或者科研等非医疗目的。
鄂ICP备2023002448号-2