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Anti-Human LETM1 Polyclonal Antibody (PTX20133)

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概述
货号PTX20133
品牌ProteoGenix
描述
Anti-Human LETM1 Polyclonal Antibody (PTX20133) is a rabbit polyclonal antibody detecting LETM1, Leucine zipper-EF-hand-containing transmembrane protein 1, Mitochondrial proton/calcium exchanger protein in ELISA, IHC, WB. Suitable for Human.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
种属反应性Human
应用ELISA, IHC, WB
宿主Rabbit
同种型IgG
克隆类型Polyclonal
免疫原E. coli - derived recombinant Human LETM1 (Leu231-Thr426).
靶标LETM1, Leucine zipper-EF-hand-containing transmembrane protein 1, Mitochondrial proton/calcium exchanger protein
纯化方式Purified by antigen affinity column.
Accession号O95202
状态Liquid
保存溶液 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景

Mitochondrial proton/calcium exchanger protein (LETM1) is a ~83 kDa protein. Plays an important role in maintenance of mitochondrial morphology and in mediating either calcium or potassium/proton antiport. Mediates proton-dependent calcium efflux from mitochondrion. Also functions as an electroneutral mitochondrial proton/potassium exchanger. Crucial for the maintenance of mitochondrial tubular networks and for the assembly of the supercomplexes of the respiratory chain. Required for the maintenance of the tubular shape and cristae organization.

1. Tamai, S. et al. (2008) Journal of cell science 121, 2588-600. PMID: 18628306
2. Jiang, D. et al. (2009) Science (New York, N.Y.) 326, 144-7. PMID: 19797662
3. Tsai, MF. et al. (2014) The Journal of general physiology 143, 67-73. PMID: 24344246
4. De Marchi, U. et al. (2014) The Journal of biological chemistry 289, 20377-85. PMID: 24898248
5. Huang, E. et al. (2017) Nature communications 8, 1399. PMID: 29123128
6. Nakamura, S. et al. (2020) Communications biology 3, 99. PMID: 32139798
7. Kaiyrzhanov, R. et al. (2022) American journal of human genetics 109, 1692-1712. PMID: 36055214
8. Austin, S. et al. (2022) EMBO reports 23, e54978. PMID: 36321428
NoteFor research use only.
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项，自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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